Tirzepatide
The least you can spend is $19.99 for 5mg at evolvebiopep. The lowest cost per mg is $1.08 at coffeeandpeppers, though that is a $649.99 cart. Across 15 vendors, 95% of listings fall between $1.08 and $10.17 per mg — a 9.4x range for the same compound.
Lowest total for a single vial — the least you can spend to start.
What Tirzepatide actually costs
Across the 15 US retail vendors we track, Tirzepatide runs from $1.08 per milligram to a median of $3.47, with the dearest tenth above $10.17. Buying at the bottom of that range rather than the middle is a 69% saving on the same compound, and today that means coffeeandpeppers.
The least you can spend to try it is $19.99 for a single vial. That figure and the cost per milligram rarely point at the same vendor — the cheapest way in is almost never the cheapest way to keep buying.
The best rate anywhere is $1.08/mg at coffeeandpeppers, on a 10-vial pack totalling 600mg for $649.99. That is a real commitment against a single vial, which is why both numbers are shown separately below rather than blended into one ranking.
Why prices vary this much
Tirzepatide prices vary by roughly 9.4× between the cheapest and dearest vendors we track, for what is nominally the same compound. Three things drive most of that gap.
Vial size. A 10mg vial at $25 and a 100mg vial at $150 look very different on the shelf, but the second is less than two thirds the price per milligram. Vendors are not obliged to make that comparable, and most do not. Normalising every listing to $/mg is the only way the field lines up.
Pack economics. Multi-vial kits routinely undercut single vials by a wide margin, because the vendor ships once and you carry the inventory. The trade is a much larger cart for a lower rate.
Positioning. Some vendors compete on price and some on presentation. With 15 vendors in the field and no obligation to disclose anything, a 193% premium over the median buys no guarantee of anything measurable.
How we work out cost per milligram
Every price here is read directly from the vendor's own store, not retyped from a screenshot or a spreadsheet, and carries the time it was read. We normalise each listing to cost per milligram by dividing the cart price by the total milligrams in the package — vial size multiplied by vial count.
Where we cannot read a dose with confidence, we publish no cost per milligram at all. Blends get no $/mg because dividing one price across several different molecules describes nothing. Capsules, nasal sprays and pre-mixed liquids are excluded from vial rankings for the same reason. A missing number means we would not stand behind it.
Common questions
What is the cheapest Tirzepatide per milligram?
$1.08/mg at coffeeandpeppers, the lowest of 15 US retail vendors we track as of the last check. The median across the field is $3.47/mg, so the cheapest listing is 69% below typical.
What is the least I can spend on Tirzepatide?
$19.99 for a single vial. That is the lowest total cart, not the lowest cost per milligram — the two are usually different vendors.
Are multi-vial packs of Tirzepatide cheaper?
Yes. The best pack rate is $1.08/mg at coffeeandpeppers, against $1.08/mg for the cheapest single vial. Packs almost always win on rate and lose on upfront cost.
How many vendors do you compare for Tirzepatide?
15 US retail vendors and 112 live listings, 112 of them in stock at the last check. We read each vendor's own store directly and re-check nightly.
Do you sell Tirzepatide?
No. We sell nothing and ship nothing. Some outbound links pay a commission, which is labelled on the row, and ranking sorts on price alone — never on what a vendor pays.